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Dietary Benefit
Brox-25 contains 25% of mixed dietary indoles. Dietary indoles support the body’s ability to eliminate toxins from the liver [1], optimize the body’s natural metabolism of hormones, and promote good estrogen (2-Hydroxy-estrone) [2,3]. Dietary indoles are important factors in promoting women’s health [4-9].

400-1600 mg daily

Product Overview
Nutritional supplements containing Dietary Indoles have been marketed since 1990. In cruciferous vegetables such as broccoli, cauliflower, cabbage, and brussels sprouts, a series of compounds react when the vegetable cell walls are broken through chopping, chewing, or juicing [10]. A wide variety of Dietary Indoles are produced in this way*. Dietary Indoles have significant physiological activity [11].
Designed Nutritional Products offers the only broccoli powder product standardized to 25% Dietary Indoles. Brox-25 includes Ascorbigen, Diindolyl-methane (DIM), and Indole-3-Carbinol (I3C). A few capsules will deliver the same Dietary Indole benefit as several pounds of cruciferous vegetables.

Most Dietary Indoles are heat and/or light sensitive. The degradation products of Dietary Indoles are considered beneficial and are the same as those formed in the stomach upon ingestion.


Dietary Indole blend. No CAS Registry Number available.

Regulatory Status
Dietary Indoles are dietary supplements under provisions of US Dietary Supplement Health and Education Act of 1994 (DSHEA).

Amounts in excess of recommended dosages may cause diarrhea.

1. McDanell, R., ETL, 1987 Food and Chemical Toxicology
25: 363-368.
2. Michnovicz, J. J.; Bradlow, H. L. 1991 Nutr. Cancer 16: 59-66. 3. Michnovicz, J. J.; Bradlow, H. L. 1990 Natl. Can. Inst. 82: 947-949
4. Michnovicz J.J., Bradlow H.L., 1993 Food Phytochemicals I: Fruits and Vegetables 282-293.
5. Sepkovic, D. et al. 1994 Steroids 59: 318-323.
6. Ge, X., Yannai S., Rennert G., Gruener N., Gares F.A. 1996
Biochem Diophys Res Commun 28:153-165.
7. Bell, M.C., ETL, 2000, Gynecologic Oncology 78: 123-129.
8. Newfield, L., ETL, 1993, Anticancer Research 13: 337-342.
9. Michnovicz J.J., Bradlow H.L., 1989 Proc. Royal Soc. Endinburgh 12: 1571-157.
10. Zeligs, M.A., 1998, Journal of Medicinal Food, 1:2, 67-82
11. Loub W.E., Wattenberg L.W., Davis D.W., 1975 J. Nat. Can. Inst. 54: 985-988.
12. Andrus, G.M., Arffman, K., 1999 United States Patent. 5895787, April 20.

* While these compounds occur naturally, they exist in extremely low quantities. All commercial sources are synthetic.

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49ers take temporary control of NFC West with 13-6 win over SeahawksBy Brian McIntyre to erase a 6-3 halftime shortage to migrate to 5-2 aboard the season, momentarily taking control of the NFC West with a 13-6 win over the Seattle Seahawks (4-3) aboard Thursday night,nike nfl jerseys.brbrAfter Steven Hauschka plus David Akers exchanged field goals within the 1st 15 min the Seahawks took a 6-3 navigate aboard a 35-yard field goal along Hauschka with 12:07 to play within the second 15 min After allowing the 49ers to earn 98 yards plus control the timer as almost nine 1/2 minutes among the 1st 15 min Seattle's defcustom baseball jerseysense stymied the 49ers within the second, limiting plus Co. to impartial 12 net yards of crime aboard nine plays in less than five minutes of possession. Even when taking over by midfield with 1:27 to activity within the half following a 38-yard punt return onward Ted Ginn, the 49ers' offense couldn't transfer the ball an inch and were forced to punt the ball behind to the Seahawks.brbrIn the final 30 minutes,whatever the 49ers would take over.brbrbrbr[Related: ]brbrOn their 1st possession of the second half, Smith directed a 10-play, 86-yard drive that ended with? a 12-yard touchdown catch-and-run forward tight baseball jerseysannihilate who avoided Seahawks defenders to sneak inside the pylon as the score. On that pedal Smith checked down to running backs Gore plus Kendall Hunter as gains of 15,eleven plus 12 yards and connected with Michael Crabtree for 10 yards aboard a critical third-and-9 activity.brbrbrbrbrbrGore was the provocative star of the night, rushing for a game-high 131 yards plus had 49ers team-highs with five receptions for 51 yards. Smith completed 14 of 23 pass attempts for 140 yards and the touchdown for Walker,but made a fussy misdeed surrounded the red zone while the 49ers had an opportunity to take a 17-6 guide eswingman jerseysarly surrounded the fourth 15 min Facing a third-and-7,agreeable coverage onward Seattle's defense forced Smith to roll out to his left where he missed a broad open Randy Moss surrounded the behind of the annihilate zone forward throwing the pellet late plus across his body. Seahawks cornerback Brandon Browner intercepted the pass to thwart a latent scoring drive.brbrFollowing a three-and-out by the Seahawks' offense Gore and Hunter chewed up virtually five minutes of the game timer on a seven-play, 39-yard pedal to set up a 28-yard field goal forward Akers that extended the 49ers' guide to seven points. The Seahnfl jerseysawks could not advance beyond their own 31-yard line on their following possession plus were forced to give the ball back to the 49ers with equitable over two minutes remaining aboard the timer plus a pair of timeouts to potentially give the offense again shot. Seattle's barricade did their jobs, stuffing Hunter, who had replaced a banged up Gore (ribs,namely expected to be fine),as runs of 2 and 0 yards. Smith attempted a quarterback draw that went for three yards and the 49ers were forced to kick A 66-yard boomer from Andy Lee pinned the Seahawks by their own 11-yard line with 1:35 to activity and no timeouts.bcheap nba jerseysr